Fluid vaccines and active principle vehicles containing a metabolizable oil

US5422109A · kind A · utility

Assignee

• SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC · FR

Inventors

• Bernard Brancq · Le Chesnay, FR
• Gerard Trouve · Castres, FR

Key dates

• Filing date: Feb 28, 1992
• Grant date: Jun 6, 1995
• Expiry date: Feb 28, 2012

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2039/55566
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to an injectable emulsion, usable as a vaccine or active principle vehicle, which has an oily continuous phase with a good tolerance under normal conditions of injection into a human or an animal, said emulsion being characterized by a viscosity of less than 800 mPas at 20.degree. C. and consisting of at least 20 to 90% of an oily adjuvant which is liquid at 4.degree. C. and contains at least one or more appropriate and pharmaceutically acceptable emulsifiers and a mixture, in any proportions, of one or more metabolizable oils with one or more non-metabolizable oils, and 10 to 80% of a hydrophilic phase containing the active principles or antigens.