On line ion contaminant removal apparatus and method for capillary electrophoresis
US5423966A · kind A · utility
17Cited by
9References
12Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Feb 15, 1994 |
| Grant date | Jun 13, 1995 |
| Priority date | — |
| Expiry date | Feb 15, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K1/26
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A Capillary Electrophoresis apparatus and method are disclosed which utilize a meltable plug in an end of the capillary tube to selectively pass small ionic contaminants electrophoretically and retain macromolecular analytes against one end of the plug until the plug is melted. When this plug is melted, the analytes and the contaminants pass through unimpeded. This permits separation of the analytes from the contaminants during electrophoretic separation and enhances instrument resolution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.