Phenyl-1,2,5-oxadiazolecarboxamide-2-oxides, their preparation and their use

US5424326A · kind A · utility

Assignee

• Cassella Aktiengesellschaft · DE

Inventors

• Karl Schonafinger · Alzenau, DE
• Helmut Bohn · Schöneck, DE

Key dates

• Filing date: May 25, 1993
• Grant date: Jun 13, 1995
• Expiry date: May 25, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D271/08
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to phenyl-1,2,5-oxadiazolecarboxamide-2-oxides of the general formula I ##STR1## in which one of the radicals R.sup.1 and R.sup.2 represents ##STR2## and the other represents ##STR3## and R.sup.3 and R.sup.4 are defined as indicated in claim 1, to processes for their preparation and to their use for the treatment of disorders of the cardiovascular system, including angina pectoris and erectile dysfunctions.