Senescent cell derived inhibitors of DNA synthesis
US5424400A · kind A · utility
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Key dates
| Filing date | Jan 3, 1994 |
| Grant date | Jun 13, 1995 |
| Priority date | — |
| Expiry date | Jan 3, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/322
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An expression vector cDNA library derived from senescent cells has been used to isolate cDNA clones that encode inhibitors of DNA synthesis. Such inhibitors play a role in cellular senescence and aging. Antisense nucleic acids reduce the inhibition of DNA synthesis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.