Patent · US Expired

Sealable vessel for containing and processing analytical samples

US5425921A · kind A · utility

78Cited by
14References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 8, 1994
Grant dateJun 20, 1995
Priority date
Expiry dateJun 8, 2014

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/25
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A sealable container for holding an analytical sample for processing is disclosed. The container includes a body with a dispensing port and an insert member with an outlet port slidably received in the body. The insert member and the body are movable relative to each other between a first position, in which the outlet port is substantially aligned with the dispensing port, and a second position, in which the outlet port is substantially out of alignment with the dispensing port. Sealing between the insert member and the body, which may take the form of O-rings, provide a substantially airtight, hermetic seal between a reaction chamber formed in the insert member and the body so that the reaction chamber can be sealed or isolated from the outside environment. The container is particularly adapted to contain the processes of nucleic acid amplification and to thereby reduce the problems of sample cross-contamination encountered in such processes. A method of processing an analytical sample using such a container is also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.