Vaccines against group C Neisseria meningitidis
US5425946A · kind A · utility
31Cited by
0References
9Claims
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Key dates
| Filing date | Aug 31, 1992 |
| Grant date | Jun 20, 1995 |
| Priority date | — |
| Expiry date | Aug 31, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/807
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An immunogenic conjugate comprising a modified group C meningococcal polysaccharide (GCMP) coupled to a carrier molecule. The GCMP is modified by O-deacetylation to a varying extent. This modified GCMP conjugate stimulates a strong immunogenic response. The antiserum, produced by immunization with this conjugate, is cross-reactive with the native polysaccharide. In addition, these antisera elicit a class of antibodies that have patent bactericidal activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.