9.alpha.-dehalogenation process
US5426198A · kind A · utility
1Cited by
3References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 31, 1990 |
| Grant date | Jun 20, 1995 |
| Priority date | — |
| Expiry date | Jan 31, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J5/0092
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention involves improved processes for the dehalogenation of 9.alpha.-halosteroids (I) ##STR1## to produce the corresponding 11.beta.-hydroxy steroids (II) ##STR2## which are known to be useful as pharmaceutical, where the improvements comprise (1) adding the 9.alpha.-halo steroid (I) to the chromium and (2) using catalytic amounts of chromium in the presence of a means of converting chromium (II) to chromium (III).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.