Patent · US Expired

Stereospecific synthesis of aldols

US5426206A · kind A · utility

3Cited by
2References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 24, 1993
Grant dateJun 20, 1995
Priority date
Expiry dateNov 24, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F7/188
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Methods are provided for preparing all four diastereomers of 2-alkyl-3-hydroxyalkanals, 2-alkyl-3-silyloxyalkanals, and the like, with high enantiocontrol, using non-aldol chemistry. The synthetic methods also provide novel, stereospecific routes to polypropinates and chiral 2-substituted-1,3 diols.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.