Radiolabeled steroids for use in radiochemical-guided surgery
US5427766A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Nov 15, 1993 |
| Grant date | Jun 27, 1995 |
| Priority date | — |
| Expiry date | Nov 15, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for detection and localization of tissues having estrogen receptors during surgery is disclosed. The method involves administering an effective amount of an estradiol derivative labeled with a radionuclide to a patient and then delaying surgery for a time interval for permitting the labeled estradiol derivative to localize in the tissue. Thereafter, an operative field of the animal is surgically accessed an the tissue within the operative filed examined with a probe to detect photon emission from the labeled estradiol derivative.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.