Patent · US Expired

Saturated hydroxyalkylquinoline acids as leukotriene antagonists

US5428033A · kind A · utility

20Cited by
3References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 10, 1991
Grant dateJun 27, 1995
Priority date
Expiry dateOct 10, 2011

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D215/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds having the formula I: ##STR1## are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.