Patent · US Expired

Heterocyclic derivatives in the treatment of Ischaemia and related diseases

US5428037A · kind A · utility

30Cited by
5References
38Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 9, 1993
Grant dateJun 27, 1995
Priority date
Expiry dateApr 9, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D333/22
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of the formula: ##STR1## wherein A, R.sup.1, R.sup.2, R.sup.3 and m are defined as in the specification or a pharmaceutically acceptable acid addition salt or N-oxide thereof, are calcium and sodium channel antagonists useful for treating mammals having a variety of disease states, such as stroke, epilepsy, hypertension, angina, migraine, arrhythmia, thrombosis, embolism, and also for treatment of spinal injuries.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.