Organic nitrates and method for their preparation

US5428061A · kind A · utility

Assignee

• Schwarz Pharma Ltd. · DE

Inventors

• Klaus Sandrock · Langenfeld, DE
• Joachim Hutter · Leverkusen, DE
• Eike Noack · Neuss, DE

Key dates

• Filing date: Sep 7, 1993
• Grant date: Jun 27, 1995
• Expiry date: Sep 7, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C323/59
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

New organic nitrate compounds, formed by condensing a nitrato alkanoic acid with a sulfur-containing amino acid or peptide, which prevent nitrate tolerance or overcome existing tolerance and which are useful for the treatment of cardiac diseases including circulatory diseases, high blood pressure, cardiac insufficiency and for dilating the peripheral vessels.