Process for antibody combining site-catalyzed epoxide formation from 1-benzyl-1-hydrocarbyl alkene molecules
US5429941A · kind A · utility
2Cited by
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10Claims
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Inventors
Key dates
| Filing date | Jan 24, 1994 |
| Grant date | Jul 4, 1995 |
| Priority date | — |
| Expiry date | Jan 24, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P17/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is disclosed by which a 1-benzyl-1-hydrocarbyl alkene substrate is catalytically converted to an epoxide. The catalyst is a monoclonal antibody or paratope-containing molecule that binds to the substrate as well as to an N-benzyl-N-hydrocarbylpiperidinium compound that is an analog to the substrate. The chemical reaction is carried out in an aqueous medium using a peroxycarboximic acid as the oxidant.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.