Insulin compounds and compositions
US5430016A · kind A · utility
15Cited by
9References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 19, 1990 |
| Grant date | Jul 4, 1995 |
| Priority date | — |
| Expiry date | Mar 19, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel insulin compounds having a desirably protracted insulin action and/or antigenicity are provided. The novel insulin compounds are represented by the formula II: ##STR1## wherein E individually represents Glu or a neutral amino acid residue which can be coded for by nucleotide sequences, N represents an amino acid residue which can be coded for by nucleotide sequences, T represents Thr or Arg, X represents Thr, Ser, Ala or OH, and Y represents OR or NR.sup.1 R.sup.2, where R, R.sup.1 and R.sup.2 individually represents hydrogen or lower alkyl, but is not present when X represents OH.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.