Piperidine derivatives, their preparation and their application in therapy
US5434169A · kind A · utility
4Cited by
5References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 27, 1993 |
| Grant date | Jul 18, 1995 |
| Priority date | — |
| Expiry date | Sep 27, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound which is a piperidine derivative of formula (I) ##STR1## in which R represents hydrogen, or unbranched or branched C.sub.1 -C.sub.6 alkyl group; and PA1 Ar represents phenyl optionally substituted with one or more radicals selected from the halogens, amino, C.sub.1 -C.sub.2 alkoxy and (C.sub.3 -C.sub.6)cycloalkyl(C.sub.1 -C.sub.2)alkoxy, or a heteroaryl group; PA1 or a pharmaceutically acceptable acid addition salt thereof; PA1 provided that when R is hydrogen Ar is not phenyl or 4 -chlorophenyl. The compounds are useful in therapy as ligands for 5-HT.sub.3 and 5-HT.sub.4 receptors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.