Imidazoles for the treatment of age-related cognitive disorders and alzheimer
US5434177A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 30, 1992 |
| Grant date | Jul 18, 1995 |
| Priority date | — |
| Expiry date | Nov 30, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to the use of a compound of formula ##STR1## wherein X is --CH.sub.2 -- or ##STR2## R.sub.1 is H, C.sub.1-5 -alkyl or benzyl, which can be substituted of unsubstituted; R.sub.2 is H, C.sub.1-4 -alkyl, C.sub.1-4 -alkenyl, OH, or C.sub.1-3 -alkoxy; R.sub.3 is H, CH.sub.3, C.sub.2 CH.sub.3, OCH.sub.3, or Hal; R.sub.4 H, CH.sub.3, C.sub.2 CH.sub.3, OCH.sub.3, or Hal, and Hal is halogen, provided that when R.sub.2 is OH or C.sub.1-3 -alkoxy then X cannot be CO or a non-toxic pharmaceutically acceptable salt thereof for the use in the treatment of age related memory impairment or cognitive disorders, particularly Alzheimer's Disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.