Monosaccharide analog-based glycosidase inhibitors
US5434266A · kind A · utility
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10Claims
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Key dates
| Filing date | Apr 29, 1993 |
| Grant date | Jul 18, 1995 |
| Priority date | — |
| Expiry date | Apr 29, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Broad spectrum glycosidase inhibitors are produced from monosaccharide lactams by conversion to amidines, amidrazones, or amidoximes. The inhibitors have the general formula: ##STR1## wherein the N and C are joined as part of a monosaccharide azaanalog ring and wherein --NRQ, together with the nitrogen and carbon atoms, form a chemical group selected from amidines, amidrazones, and amidoximes.
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