New preparation of placenta collagen, their extraction method and their applications
US5436135A · kind A · utility
93Cited by
4References
15Claims
0Family size
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Key dates
| Filing date | Jan 7, 1991 |
| Grant date | Jul 25, 1995 |
| Priority date | — |
| Expiry date | Jan 7, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/40
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Human or animal placenta is subjected to moderate enzymatic digestion, in particular with pepsin at an acid pH, then, after separation of the residual tissue the impurities are separated at a moderately acid pH, the collagen is precipitated at a neutral pH, redissolved and the residual impurities precipitated at an acid pH. The collagen obtained can be brought back to a neutral pH and dried in the form of fibres. Completely transparent, physiological and hemocompatible gels and solutions can be prepared. Applications for the fabrication of contact lenses and implants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.