Inhibitors of farnesyl-protein transferase
US5436263A · kind A · utility
0Cited by
10References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 22, 1994 |
| Grant date | Jul 25, 1995 |
| Priority date | — |
| Expiry date | Mar 22, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/352
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FPTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.