Antibodies to the lipopolysaccharide bonding opsonin septin
US5436321A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jul 31, 1992 |
| Grant date | Jul 25, 1995 |
| Priority date | — |
| Expiry date | Jul 31, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An antibody to septin, in which septin is an opsonin. Septin is isolated from human serum and is present at high levels in normal serum in distinction to the acute phase protein lipoprotein binding protein (LBP). Septin is an opsonin that is capable of binding to lipopolysaccharide to form a complex that is recognized by a receptor on monocytes, macrophage cells and polymorphonuclear cells, and that possesses an apparent molecular weight of about 90 kD as determined by SDS-PAGE analysis. Utilities of the antibody are provided, and testing procedures, materials in kit form, recombinant materials and procedures, and compositions are likewise set forth.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.