Indolocarbazole derivatives, processes for their preparation and compositions containing them

US5438050A · kind A · utility

Assignee

• Godecke Aktiengesellschaft · DE

Inventors

• Jurgen Kleinschroth · Denzlingen, DE
• Johannes Hartenstein · Kirchzarten, DE
• Hubert Barth · Emmendingen, DE
• Christoph Schachtele · Glückstadt, DE
• Claus Rudolph · Denzlingen, DE
• Gunter Weinheimer · Denzlingen, DE
• Hartmut Osswald · Völklingen, DE

Key dates

• Filing date: Jan 21, 1994
• Grant date: Aug 1, 1995
• Expiry date: Jan 21, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

New indolocarbazoles of formula: ##STR1## or a pharmaceutically acceptable salt thereof, processes for their preparation, compositions containing, and methods for using the composition for the inhibition of protein kinases, such as protein kinase C, for the prevention and/or treatment of heart and blood vessel diseases such as thromboses, arterioscleroses, hypertension, or for inflammatory processes, allergies, cancers, viral diseases, and certain degenerative damages of the central nervous system are disclosed.