Imidazopyridines as angiotensin II antagonists

US5438063A · kind A · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Mathias Osswald · Zwingenberg, DE
• Werner Mederski · Zwingenberg, DE
• Dieter Dorsch · Ober-Ramstadt, DE
• Pierre Schelling · Mühltal, DE
• Norbert Beier · Reinheim, DE
• Ingeborg Lues · Darmstadt, DE
• Klaus-Otto Minck · Ober-Ramstadt, DE

Key dates

• Filing date: Jun 6, 1994
• Grant date: Aug 1, 1995
• Expiry date: Jun 6, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel imidazopyridine derivatives of formula I ##STR1## wherein ##STR2## and R.sup.1, R.sup.2, R.sup.3, R.sup.4, X and Y are as defined herein, and their salts, exhibit antagonistic properties toward angiotensin II and can be used for the treatment of hypertension, aldosteronism, cardiac insufficiency and increased intraocular pressure, and of disorders of the central nervous system.