Method of treating colon disturbances with pharmaceutical compositions containing imidazol-1-yl compounds

US5438068A · kind A · utility

Assignee

• Kali-Chemie Pharma GmbH · DE

Inventors

• Christian Eeckhout · Winsen (Aller), DE
• Ulf Preuschoff · Laatzen, DE
• Samuel David · Dorval, CA

Key dates

• Filing date: Nov 3, 1993
• Grant date: Aug 1, 1995
• Expiry date: Nov 3, 2013

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P1/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Use of imidazol-1-yl compounds of the general formula I ##STR1## wherein R.sup.1 denotes lower alkyl or hydrogen; PA1 m represents 2 or 3, and PA1 n represents 2 or 3; or a physiologically acceptable acid addition salt thereof for treating functional disturbances of the lower intestinal tract in larger mammals and humans associated with increased pain sensitivity and/or anomalies in stool passage in the colon region.