Chamber for freeze-drying by cryosorption

US5438838A · kind A · utility

Assignee

• Leica AG · AT

Inventors

• Hellmuth Sitte · Laa an der Thaya, AT
• Klaus Neumann · Niederwerrn, DE
• Ludwig Edelmann · Premich, DE
• Helmut Haessig · Homburg, DE
• Heinrich Kleber · Wien, AT

Key dates

• Filing date: Jun 1, 1994
• Grant date: Aug 8, 1995
• Expiry date: Jun 1, 2014

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N1/42
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A chamber system for cryosorption freeze-drying of biological specimens in a Dewar vessel, comprises a chamber having a cylindrical metal wall and fitted within the Dewar vessel, a lower outer edge of which chamber is connected in a vacuum-tight manner to a lower edge of a metallic rotational component, the metallic rotational component having a bottom contact surface, which bottom contact surface corresponds with a complementary top contact surface on top of a cylindrical body around which liquid nitrogen flows and cools the metallic rotational component, the rotational component having a chamber to receive a drying agent for conducting cryosorption, for example a molecular screen, as well as a connection to the drying chamber. The upper edge of the metal wall or a ring connected thereto in a vacuum-tight manner is situated outside the Dewar vessel and is therefore approximately at ambient temperature and has a vacuum connection for the connection of commercially available vacuum components. The opening at the top of the ring is preferably sealable in a vacuum-tight manner by a commercially available O-ring in conjunction with a cover.