Biological imaging emulsions containing alkyl- or alkylglycerophosphoryl choline surfactants and methods of use
US5439669A · kind A · utility
3Cited by
14References
14Claims
0Family size
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Key dates
| Filing date | Nov 24, 1993 |
| Grant date | Aug 8, 1995 |
| Priority date | — |
| Expiry date | Nov 24, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Oil and water emulsions containing alkylphosphoryl choline or alkylglycerophosphoryl choline surfactants are disclosed. The surfactants have the following general structures: ##STR1## In the above general structures, R.sub.1, R.sub.2 or R.sub.3 is alkyl, alkenyl, fluoroalkyl and alkenyl; and PC is the phosphoryl choline. The emulsions are useful as oxygen transport agents, artificial bloods or red blood cell substitutes. The emulsions are also useful as contrast agents for biological imaging by the modalities of nuclear magnetic resonance, x-ray and ultra sound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.