Leukotriene B.sub.4 antagonists
US5439937A · kind A · utility
3Cited by
7References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 3, 1994 |
| Grant date | Aug 8, 1995 |
| Priority date | — |
| Expiry date | Mar 3, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to compounds of Formula I and the stereoisomers and pharmaceutically acceptable salts thereof ##STR1## wherein R is alkyl, alkenyl, alkynyl, or cycloalkylalkyl; PA1 R.sup.1 is alkyl; PA1 R.sup.2 is hydrogen, alkyl; PA1 R.sup.6 is alkyl; PA1 n is 1 to 5; PA1 p is 0 to 6; PA1 x is 0 or 2; and R.sup.4 and R.sup.5 are independently hydrogen or alkyl or together with N form a cycloalkylamine. The compounds of Formula I are leukotriene B.sub.4 antagonists and are useful as anti-inflammatory agents and in treating disease conditions mediated by LTB.sub.4.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.