Patent · US Expired

Leukotriene-B.sub.4 derivatives, process for their production and their use as pharmaceutical agents

US5440044A · kind A · utility

2Cited by

0References

2Claims

0Family size

Assignee

SCHERING CORPORATION · US

Inventors

Josef Heindl · Berlin, DE
Werner Skuballa · Berlin, DE
Bernd Buchmann · Hohen Neuendorf, DE
Wolfgang Frohlich · Berlin, DE
Roland Ekerdt · Berlin, DE
Claudia Giesen · Berlin, DE

Key dates

Filing date	Dec 3, 1993
Grant date	Aug 8, 1995
Priority date	—
Expiry date	Dec 3, 2013

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D213/81
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to a leukotriene-B.sub.4 analog according to formula I ##STR1## in which R.sup.1 is a COOR.sup.2 group, wherein R.sup.2 is a C.sub.2-4 -alkyl group; PA1 B is a C.sub.1-3 -alkylene group, a radical ##STR2## wherein R.sup.3 is a hydrogen atom or a carboxy or methoxycarbonyl group; ##STR3## . . . is a single or double bond; or optionally, their salts with physiologically compatible bases. The present invention also relates to the production of the latter leukotriene-B.sub.4 analogs and their use as pharmacological agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.