Method of delivering micellular particles encapsulating chemotherapeutic agents to tumors in a body
US5441745A · kind A · utility
33Cited by
16References
17Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 22, 1984 |
| Grant date | Aug 15, 1995 |
| Priority date | — |
| Expiry date | Oct 22, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/829
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method is provided for delivering micellular particles containing chemotherapeutic agents and a marker to tumors within a body for the diagnosis and treatment of such tumors. The micellular particles are small, less than 2000 .ANG. and incorporate pure, neutral phospholipid molecules in their external surface. Enhanced delivery of the micellular particles containing marker and chemotherapeutic agents may be achieved by introducing an initial group of positively charged micellular particles to block the reticuloendothelial cells present in the body.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.