Treatment of infection by enveloped virus with calix(N)arene compounds
US5441983A · kind A · utility
13Cited by
1References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 6, 1992 |
| Grant date | Aug 15, 1995 |
| Priority date | — |
| Expiry date | Aug 6, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for inhibiting cell infection by an enveloped virus, by administering to an infection site, a therapeutically effective amount of a calix(n)arene compound derivatized, at its ring positions meta to the bridge attachements to the ring, with polar substitutent having a terminal carboxylate, phosphate, or sulfonate groups, including esters and amides which are cleavable in vivo. The compound may be administered orally, or topically, e.g., for treatment of herpes virus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.