Stabilized polymer film coated compounds and stabilized formulations in compressed from using same

US5442008A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Werner Fulberth · Frankfurt am Main, DE
• Richard Leeb · Kelkheim, DE
• Manfred Radau · Kelkheim, DE
• Willi Stammberger · Hofheim, DE

Key dates

• Filing date: Feb 10, 1994
• Grant date: Aug 15, 1995
• Expiry date: Feb 10, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Stabilized medicinal substances, a process for the preparation thereof, and stable medicinal formulations Stabilized compounds of the formula I ##STR1## in which R, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the stated meanings, and a process for the preparation thereof, are described. The stabilized compounds are suitable for the manufacture of medicinal formulations. The formula I compounds are stabilized by a polymeric protective coating before being compressed in tablet form.