Patent · US Expired

Human leukemia inhibitory factor

US5443825A · kind A · utility

8Cited by

1References

11Claims

0Family size

Assignee

AMRAD Corporation Limited · AU

Inventors

David Gearing · Melbourne, AU
Nicholas Martin Gough · Melbourne, AU
Douglas Hilton · Melbourne, AU
Julie Ann King · Melbourne, AU
Donald Metcalf · Melbourne, AU
Edouard Collins Nice · Melbourne, AU
Nicos A. Nicola · Melbourne, AU
Richard J. Simpson · Melbourne, AU
Tracy Willson · Melbourne, AU

Key dates

Filing date	Sep 22, 1992
Grant date	Aug 22, 1995
Priority date	—
Expiry date	Sep 22, 2012

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2740/13043
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Leukemia-inhibitory factor (LIF) has been produced in essentially pure form from murine or human sources. A method of purifying this LIF is disclosed, as well as polypeptides having LIF activity which are not identical in amino acid sequence to any naturally occurring form of LIF. The polypeptides can be used for hindering the proliferation of myeloid Leukemia cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.