Hypertonic isochloremic formulations for treatment of hypovolemic and circulatory shock
US5443848A · kind A · utility
27Cited by
5References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 24, 1993 |
| Grant date | Aug 22, 1995 |
| Priority date | — |
| Expiry date | Sep 24, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to hypertonic crystalloid resuscitation fluids particularly useful in treating hemorrhagic shock. A pharmaceutical formulation prepared and selected ratios of sodium chloride and sodium acetate with a total osmolar concentration exceeding 500 mOsm can be used as a small volume resuscitation fluid which has little effect on plasma chloride levels. Arterial pressure is improved to the point of sustaining oxygen supply to tissues and organs with a significant increase in oxygen delivery and consumption.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.