Species-specific oligonucleotides for bifidobacteria and a method of detection using the same
US5443951A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 20, 1993 |
| Grant date | Aug 22, 1995 |
| Priority date | — |
| Expiry date | Jul 20, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/689
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Oligonucleotides which specifically hybridize to rRNAs of Bifidobacterium infantis, Bifidobacterium bifidum, Bifidobacterium adolescentis, Bifidobacterium breve, and Bifidobacterium longum represented by the sequences of formulae (I) to (V), respectively, or sequences complementary thereto: EQU UAUCGGGGAGCAAGCGUGA (I)SEQ ID NO: 1 EQU UCGGAUCGGAGCCUGC (II)SEQ ID NO: 4 EQU CGCUUUUGACUGGGAGC (III)SEQ ID NO: 7 EQU UGUGUUGAGUGUACCUU (IV)SEQ ID NO: 10 EQU UAUCGGGGAGCAAGCGAGA (V)SEQ ID NO: 13 and a method of species-specifically detecting species of the genus Bifidobacterium of human origin comprising using these oligonucleotides as a labeled probe.
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