Method for diagnosing cellular aging or inflammation condition of keratinocytes, and kit for implementing such method
US5443961A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 19, 1993 |
| Grant date | Aug 22, 1995 |
| Priority date | — |
| Expiry date | Oct 19, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/904
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Method for diagnosing a cellular aging or inflammation condition of keratinocytes of the skin or a pilous follicle in a person, or for diagnosing the efficiency of a treatment intended to combat said condition. To this effect, the concentration or activity of certain markers (catalase, glutathion or glutathion peroxydase) is compared in the keratinocytes suspected of being pathological and the keratinocytes of a reference non pathological area. The pathological condition intensifies the activity of the catalase, or reduces the activity of other markers. Application particularly to the diagnosis of alopecia, and to the estimation of the efficiency of a treatment of baldness with minoxidil in a given individual.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.