Pyranones
US5443970A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 17, 1992 |
| Grant date | Aug 22, 1995 |
| Priority date | — |
| Expiry date | Sep 17, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the separation of at least one isomer from a mixture of isomers of a tetrahydropyran-2-one, having at least two chiral centres, which comprises selective reaction of at least one isomer with a reagent catalysed by a hydrolase enzyme whereby at least one isomer is preferentially converted into a distinct chemical species from the other isomers so that it is susceptible of separation by an appropriate chemical or physical separation process in which the tetrahydropyranone is of Formula (1): ##STR1## wherein: Z is --H or a protecting group susceptible of reaction with the reagent under the influence of the enzyme; and PA1 Y is optionally substituted hydrocarbyl.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.