Peptide compounds derived from boronic acid
US5444049A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 22, 1994 |
| Grant date | Aug 22, 1995 |
| Priority date | — |
| Expiry date | Feb 22, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound of formula (I): ##STR1## in which: R.sub.1 represents hydrogen or acyl, alkyl, benzyl, alkoxycarbonyl, benzyloxycarbonyl, phenoxycarbonyl, 5-[(dimethyl)amino]naphthylsulfonyl, alkoxycarbonylmethyl or carboxymethyl, PA0 R.sub.2 represents hydrogen or phenyl, substituted or unsubstituted benzyl, 3-thienylmethyl, 2-pyridylmethyl, diphenylmethyl, fluorenyl, naphthylmethyl, benzocyclobutyl, (dicyclopropylmethyl)methyl, indanyl or (C.sub.3 -C.sub.7 cycloalkyl)methyl, PA0 R'.sub.2 represents hydrogen or benzyl or alternatively PA0 R.sub.2 and R'.sub.2 together represent C.sub.6 H.sub.5 --CH.dbd., PA0 R.sub.3 represents substituted alkyl or guanidinophenyl, amidinophenyl, aminophenyl, guanidinobenzyl, amidinobenzyl, aminobenzyl or cycloalkyl, PA0 R.sub.4 and R.sub.5 each represent hydrogen or alkyl, or ##STR2## forms a boronic ester of pinanediol, A represents any one of the groups as defined in the description. Medicinal products.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.