Iontophoresis device and method using a rate-controlling electrically sensitive membrane
US5445607A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 15, 1992 |
| Grant date | Aug 29, 1995 |
| Priority date | — |
| Expiry date | Oct 15, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/0448
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An iontophoresis device comprising a drug reservoir containing the drug in ionic form and in communication with the skin, a skin permeation enhancing agent contained in the reservoir or in a second reservoir also in communication with the skin, an electrode in contact with the drug, another electrode in contact with the skin, a D.C. power source connected to the electrodes and an electrically sensitive membrane interposed between the reservoir and the skin that is impermeable to drug in the absence of a voltage difference between the electrodes and permeable to the drug in the presence of a voltage difference. The skin permeation enhancing agent eliminates the skin as a rate-controlling element, thus making the rate of drug administration dependent upon the membrane permeability, which in turn is controlled electrically.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.