Process for the preparation of microspheres made of a biodegradable polymeric material
US5445832A · kind A · utility
88Cited by
6References
7Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 16, 1992 |
| Grant date | Aug 29, 1995 |
| Priority date | — |
| Expiry date | Jul 16, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K7/23
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The process is aimed at providing a composition designed for the sustained and controlled release of medicamentous peptide substances, obtained in the form of microspheres of a biodegradable polymeric material incorporating said medicamentous substance. It consists in converting first a water-soluble peptide or peptide salt into a water-insoluble peptide, respectively peptide salt. The following steps include preparing an organic-aqueous emulsion and then extracting the organic solvent in an excess of aqueous medium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.