Alcohol-ester separation by recrystallization
US5445963A · kind A · utility
3Cited by
5References
8Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Feb 26, 1991 |
| Grant date | Aug 29, 1995 |
| Priority date | — |
| Expiry date | Feb 26, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/876
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is disclosed for the separation of an enantiomerically enriched 1-tosyloxy-2-acyloxy-3-butene and an enantiomerically enriched 1-tosyloxy-2-hydroxy-3-butene from a first mixture containing both compounds. The process includes the steps of: (a) forming a solution of the mixture in an organic solvent; (b) bringing the solution formed in (a) to a temperature wherein most of the enantiomerically enriched 1-tosyloxy-2-hydroxy-3-butene precipates, leaving in solution most of the enantiomerically enriched 1-tosyloxy-2-acyloxy-3-butene; and (c) separating the precipitate formed in (b) from the solution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.