Magnetically assisted binding assays using magnetically labeled binding members
US5445970A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Dec 1, 1994 |
| Grant date | Aug 29, 1995 |
| Priority date | — |
| Expiry date | Dec 1, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/806
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides assay methods for performing binding assays, wherein the detectable label is a magnetically responsive material. Direct and indirect, competitive and sandwich assay formats are used to partition the magnetically attractable label between a solid phase and a fluid phase in proportion to the presence or amount of analyte in the test sample. The magnetic responsiveness of the magnetically attractable label in one or both phases results in the exertion of a force upon the label. By determining the extent of the force or influence of the force exerted upon the label, the amount of the analyte in the test sample is determined.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.