Patent · US Expired

2-[(substituted) methylene]cephalosporin sulfones as antiinflammatory, antidegenerative and antithrombin agents

US5446037A · kind A · utility

8Cited by
4References
30Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 13, 1993
Grant dateAug 29, 1995
Priority date
Expiry dateDec 13, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D501/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention relates to 2-[(substituted)methylene]cephalosporin sulfones and in particular 2-[(heteroaryl substituted)methylene]cephalosporin sulfones which are effective elastase inhibitors as well as effective thrombin inhibitors and therefore are useful as anti-inflammatory, anti-degenerative and anti-thrombin agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.