Process for the production of 7-acylindoles
US5446162A · kind A · utility
0Cited by
2References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 26, 1994 |
| Grant date | Aug 29, 1995 |
| Priority date | — |
| Expiry date | Jul 26, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the production of 7-acylindoles of the general formula: ##STR1## starting from indoline of the formula: ##STR2## Indoline is cyanized in a first stage to 7-cyanoindoline of the formula: ##STR3## The latter is catalytically dehydrogenated in a second stage to 7-cyanindole of the formula: ##STR4## The latter is then acylated in a third stage with an organometallic compound of the formula: EQU R--Q V into the end product according to formula I.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.