Patent · US Expired

.beta.-glucuronidase inhibitor

US5447719A · kind A · utility

9Cited by
0References
12Claims
0Family size

Assignee

Inventor

Key dates

Filing dateMar 25, 1993
Grant dateSep 5, 1995
Priority date—
Expiry dateMar 25, 2013

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A .beta.-glucuronidase inhibitor comprising at least one compound selected from the group consisting of baicalin, oroxylin A-7-O-glucuronide and luteolin-3'-glucuronide; an extract of scutellaria root (baikal skullcap; Scutellariae Radix) and/or schizonepeta spike (Japanese catnip; Schizonepelae Spica); or a Chinese and Japanese traditional prescription comprised of scutellaria root (baikal skullcap; Scutellariae Radix) and/or schizonepeta spike (Japanese catnip; Schizonepelae Spica) as a crude drug. The .beta.-glucuronidase inhibitor can relieve the adverse effect, especially diarrhea, caused in the administration of a compound represented by the following formula I ##STR1##

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.