Method for the purification or removal of retroviruses using sulfated cellulose
US5447859A · kind A · utility
40Cited by
13References
5Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jul 16, 1993 |
| Grant date | Sep 5, 1995 |
| Priority date | — |
| Expiry date | Jul 16, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/13022
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods and compositions useful for the separation of viruses, including retroviruses and vital vectors, from preparations are disclosed. Sulfated oligosaccharides with at least about 6 .mu.moles sulfate per gram of oligosaccharide are provided. In one aspect, a sulfated oligosaccharide of the present invention may be used in the purification of a virus, such as a lipid envelope virus. The present invention also discloses methods for the removal of a contaminating virus from a preparation, such as biologic therapeutics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.