Erection-inducing methods and compositions
US5447912A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 16, 1993 |
| Grant date | Sep 5, 1995 |
| Priority date | — |
| Expiry date | Aug 16, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/183
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions for inducing penile erections, sufficient for vaginal penetration, in a human male suffering from impotence are provided. Kits containing the compositions in containers for single dosage administration are provided. Compositions for treating impotence that is of psychogenic or neurogenic origin contain a neuropeptide, vasoactive intestinal peptide and/or peptide N-terminal histidine C-terminal methioneamide and are formulated in a pharmaceutically acceptable carrier that has a pH of about 2 to about 4.5, preferably between about 2 and about 3.5, and most preferably about 3. Compositions for treating impotence of almost origin, including severe atherosclerosis, contain a neuropeptide, vasoactive intestinal peptide and/or peptide N-terminal histidine C-terminal methioneamide, and an .alpha.-adrenergic blocker, such as phentolamine or prazosin. In practicing the methods, the composition is administered by intracavernosal injection accompanied by or followed by sexual stimulation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.