Method of space charge control for improved ion isolation in an ion trap mass spectrometer by dynamically adaptive sampling
US5448061A · kind A · utility
30Cited by
5References
23Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jan 10, 1994 |
| Grant date | Sep 5, 1995 |
| Priority date | — |
| Expiry date | Jan 10, 2014 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/0031
- WIPO fieldElectrical machinery, apparatus, energy
- WIPO sectorElectrical engineering
Abstract
A method of using a quadrupole ion trap mass spectrometer for high resolution mass spectroscopy is disclosed. In the preferred embodiment, the space charge in the ion trap is controlled to high accuracy. This is done by using a prescan of the trap before each analytical scan, where the ionization parameters used in the prescan are not fixed, but rather are based on the previous analytical scan. The method is especially useful in connection with performance of high resolution MS/MS experiments of the type described in the inventor's prior U.S. Pat. No. 5,198,665.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.