Method for measuring specific binding assays
US5449621A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jan 21, 1994 |
| Grant date | Sep 12, 1995 |
| Priority date | — |
| Expiry date | Jan 21, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/111666
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An automated patient sample analysis instrument uses assay cartridges which are pre-loaded with all reactants needed to perform an assay. Photometric measurements are performed on the cartridges while spinning at variable speeds in a centrifuge. Both axial and transverse measurements can be made on the cartridges. Multiple optical channels can be read by single detector. The instrument is well suited for low volume and for use by unskilled individuals. The photometric measurements are made by dividing the width of a measurement window into n intervals, measuring an optical result in one of the n intervals in each of n rotations of the cartridge, repeating the measurement process x times, summing or averaging the x results for each of the n intervals and selecting y of the largest resultant averaged or summed measurements as representative of the maximum measurement for the window.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.