Patent · US Expired

Atrial natriuretic peptide clearance inhibitors which resist degradation

US5449662A · kind A · utility

36Cited by
7References
10Claims
0Family size

Assignee

Inventor

Key dates

Filing dateFeb 20, 1992
Grant dateSep 12, 1995
Priority date
Expiry dateFeb 20, 2012

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds with natriuretic, diuretic and/or vasodilation activity which enhance the function of an endogenous ANP are provided. These compounds are capable of both binding to the clearance receptors for ANP and of inhibition of endopeptidase 24.11, an enzyme believed responsible for ANP clearance.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.