Production of taxol
US5451392A · kind A · utility
11Cited by
10References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 3, 1992 |
| Grant date | Sep 19, 1995 |
| Priority date | — |
| Expiry date | Mar 3, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D305/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Taxol and radiolabelled taxol are produced from sterilized Yew trees by contacting sterilized Yew tree stock with a reactor solution comprising a reducing agent, an energy source, a buffer to maintain pH in the range of 6.5 to 7.5, a taxol precursor, and a steroid inhibitor. A radiolabelled precursor may be included in the reactor solution to produced radiolabelled taxol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.