Substituted cyclohexane derivatives for the treatment of diseases

US5451573A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Horst Hemmerle · Lorsch, DE
• Peter Schindler · Rodgau, DE
• Roland Utz · Messel, DE
• Robert Rippel · Hofheim, DE
• Andreas Herling · Bad Camberg, DE

Key dates

• Filing date: Sep 7, 1993
• Grant date: Sep 19, 1995
• Expiry date: Sep 7, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/16
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Substituted cyclohexane derivatives for the treatment of diseases Esters of cyclohexane derivatives of the formula I ##STR1## in which A--B, R.sup.3, R.sup.4, R.sup.5, Y and Z have the meanings indicated, for use as inhibitors of the glucose-6-phosphatase system of the liver in mammals are described. The compounds are suitable for the production of pharmaceutical preparations.